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HFCS – More to it than we thought

Also see:
Sugar (Sucrose) Restrains the Stress Response
Thumbs Up: Fructose

“Much of the current concern about the dangers of fructose is focussed on the cornstarch- derived high fructose corn syrup, HFCS. Many studies assume that its composition is nearly all fructose and glucose. However, Wahjudi, et al. (2010) analyzed samples of it before and after hydrolyzing it in acid, to break down other carbohydrates present in it. They found that the carbohydrate content was several times higher than the listed values. “The underestimation of carbohydrate content in beverages may be a contributing factor in the development of obesity in children,” and it’s especially interesting that so much of it is present in the form of starch-like materials.” -Ray Peat, PhD

FASEB 562.1
Carbohydrate Analysis of High Fructose Corn Syrup (HFCS) Containing Commercial Beverages
Paulin Nadi Wahjudi, Emmelyn Hsieh, Mary E Patterson, Catherine S Mao, and WN Paul Lee
The carbohydrate analysis of HFCS is based on methods which first hydrolyze the syrup into simple sugars before quantitative analysis. We have examined whether HFCS can be hydrolyzed under the same conditions suitable for hydrolyzing sucrose. A new GC/MS method for the quantitation of fructose and glucose as their methoxyamine derivatives and 13C labeled recovery standards was used to determine the carbohydrate content of HFCS in 10 commercial beverages. Samples were analyzed before and after acid hydrolysis. The carbohydrate contents in commercial beverages determined without acid hydrolysis were in agreement with the carbohydrate contents provided on the food labels. However, the carbohydrate contents of beverages determined after acid hydrolysis were substantially (4–5 fold) higher than the listed values of carbohydrates. As fructose and glucose in HFCS may exist as monosaccharides, disaccharides and/or oligosaccharides, analysis of the carbohydrate content of HFCS containing samples may yield widely different results depending on the degree of hydrolysis of the oligosaccharides. With inclusion of mild acid hydrolysis, all samples showed significantly higher fructose and glucose content than the listed values of carbohydrates on the nutrition labels. The underestimation of carbohydrate content in beverages may be a contributing factor in the development of obesity in children.

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4 Responses

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  1. Wayde Curran says

    Any idea if the fructose powder derived from corn has the same problem with starch polymers in it and if it’s caloric value is also under estimated like the HFCS?

  2. Team FPS says

    I suspect it would have starch polymers. I think Dr. Peat mentioned this actually in an interview about sugar/starch/glycemia with East West healing. He is very critical of supplements in articles not appearing on his website. I have yet to find a “pure” fructose powder that at least one client didn’t react to.

  3. tommo littlewood says

    I guess one of the overlooked factors is that most of the corn is also a GM source.

  4. Team FPS says

    Yes. Mercury content of HFCS is another concern.



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