Lancet. 2001 Aug 4;358(9279):351-5. Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study. Schatz IJ, Masaki K, Yano K, Chen R, Rodriguez BL, Curb JD. BACKGROUND: A generally held belief is that cholesterol concentrations should be kept low to lessen the risk of cardiovascular disease. However, studies of the [...]
Lancet. 2000 Sep 9;356(9233):930-3. The endotoxin-lipoprotein hypothesis. Rauchhaus M, Coats AJ, Anker SD. The advent of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) has revolutionised the treatment of hypercholesterolaemia. Statin treatment, by lowering the atherogenic lipoprotein profile, reduces morbidity and mortality in patients with cardiovascular disease. Treatment with simvastatin causes a reduction of events of new-onset heart [...]
J Clin Endocrinol Metab. 1997 Oct;82(10):3421-4. Both hypothyroidism and hyperthyroidism enhance low density lipoprotein oxidation. Sundaram V, Hanna AN, Koneru L, Newman HA, Falko JM. Hypothyroidism is frequently associated with hypercholesterolemia and an increased risk for atherosclerosis, whereas hyperthyroidism is known to precipitate angina or myocardial infarction in patients with underlying coronary heart disease. We [...]
by Barry Groves http://www.second-opinions.co.uk/immunity3.html There is a substantial amount of evidence that relatively low cholesterol levels in apparently healthy individuals is associated with increased subsequent mortality from cancer. It is also associated with other, non-heart related deaths. A group at the Center for Clinical Pharmacology, University of Pittsburgh, Pennsylvania, tested whether the effectiveness of their [...]
