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Synthroid Sucks! The Rallying Cry of Thyroid Patients vs. Clueless Doctors

By Janie Bowthorpe The advent of the Internet plopped into the laps of hapless hypothyroid patients like gold by the turn of this century-the seed of a now-fervent global movement against a 50-year medical scandal. In 1955, Knoll Pharmaceuticals of Germany developed the ever well-known Synthroid, a synthetic T4-only thyroid storage hormone pill. It was […]

Benefits of Aspirin

Also see: Ray Peat, PhD on Aspirin Aspirin and Exercise A Cancer Treatment in Your Medicine Cabinet? PUFA Promote Cancer Arachidonic Acid’s Role in Stress and Shock Sunburn, PUFA, Prostaglandins, and Aspirin Phospholipases, PUFA, and Inflammation Dietary PUFA Reflected in Human Subcutaneous Fat Tissue Toxicity of Stored PUFA PUFA – Accumulation and Aging Brain Swelling […]

Is Gwyneth Paltrow’s Diet to Blame for Bone Disease?

By LUCHINA FISHER June 29, 2010 Gwyneth Paltrow’s announcement that she has osteopenia, a possible precursor to the bone-thinning disease osteoporosis — conditions usually found in older women — has some wondering if her extreme diet and exercise regimen is to blame. In her online newsletter GOOP, Paltrow, who is 37, revealed that she was […]

Sustainability of 180 Nutrition Program

Hope you are well. Wanted to shoot you an email to update you. Still doing well. Have reached a point that I can stray and a meal and do fine as long as I am strict before and after. Some veggies I have to just stay away from completely. Weight is stable. Still like what […]

The Randle Cycle (Glucose-Fatty Acid Cycle)

Also see: Master List – Ray Peat, PhD Interviews Ray Peat, PhD on Low Blood Sugar & Stress Reaction Aldosterone, Sodium Deficiency, and Insulin Resistance Ray Peat, PhD Quotes on Therapeutic Effects of Niacinamide Diabetes: Conversion of Alpha-cells into Beta-cells Errors in Nutrition: Essential Fatty Acids Women, Estrogen, and Circulating DHA Insulin Inhibits Lipolysis PUFA […]

Genes, Carbon Dioxide and Adaptation

Source by Ray Peat, PhD “Over the oxygen supply of the body carbon dioxide spreads its protecting wings.” Friedrich Miescher, Swiss physiologist, 1885 To reach useful simplicities, we usually have to sift through the accumulated rationalizations previous generations have produced to justify doing things their way. If we could start with an accurate understanding of […]

Mitochondria and mortality

by Ray Peat, PhD Diet, exercise, and medicine, damaging or repairing respiratory metabolism MAIN IDEAS AND CONTEXTS Lactic acid and carbon dioxide have opposing effects. Intense exercise damages cells in ways that cumulatively impair metabolism. There is clear evidence that glycolysis, producing lactic acid from glucose, has toxic effects, suppressing respiration and killing cells. Within […]

Stress and Water

by Ray Peat, PhD The biological idea of stress refers to the difficulty of adapting, and this involves energy, structure, and insight/orientation. Given enough energy, we can often adjust our structure to achieve full adaptation, and with insight, we can minimize the amount of energy and structural change needed, for example just by a change […]

German Volume Training

A new look at an old way to get big and strong by Charles Poliquin Supersets and tri-sets allow you to perform a lot of work in a short period of time. The rest-pause method allows you to use heavier weights so you can recruit the higher-threshold muscle fibers, and eccentric training enables you to […]

What if there was a Cure for Alzheimer’s Disease and No One Knew?

WHAT IF THERE WAS A CURE FOR ALZHEIMER’S DISEASE AND NO ONE KNEW? A Case Study by Dr. Mary Newport July 22, 2008 There is a growing epidemic of obesity, type II diabetes, cardiovascular disease, and predictions that 15,000,000 people in the United States alone will have Alzheimer’s Disease by the year 2050. In 2001, […]

Sugar (Sucrose) Restrains the Stress Response

Also see: PUFA Promote Stress Response; Saturated Fats Suppress Stress Response Ray Peat, PhD on Low Blood Sugar & Stress Reaction Thumbs Up: Fructose Theurapeutic Honey – Cancer and Wound Healing Carbohydrates and Bone Health Carbohydrate Lowers Exercise Induced Stress Carbohydrate Lowers Serotonin from Exercise HFCS – More to it than we thought Protection from […]

High Cholesterol and Metabolism

Also see: Ray Peat, PhD on Thyroid, Temperature, Pulse, and TSH Thyroid Status and Cardiovascular Disease Protect the Mitochondria PUFA Promote Cancer The Cholesterol and Thyroid Connection High Blood Pressure and Hypothyroidism A Cure for Heart Disease Hypothyroidism and A Shift in Death Patterns The Truth about Low Cholesterol Thyroid Status and Oxidized LDL Inflammatory […]

Low Carb Diet – Death to Metabolism

Also see: Sucrose substitution in prevention and reversal of the fall in metabolic rate accompanying hypocaloric diets Sugar and body weight regulation. rethink how you exercise: An interview with Rob Turner – Part 1 rethink how you exercise: An interview with Rob Turner – Part 2 Low carb + intensive training = fall in testosterone […]

Quick Hits: Using the Contrast Method

There are infinite ways to modify acute training variables. One way which I have been discussing lately (see Wave Loading and 6-12-25) is the manipulation of sets/reps within a workout. The next method I’d like to discuss is the contrast method developed by Charles Poliquin. The contrast method alternates between sets from two different training […]

General Program Design Principles

Exercise professionals are equipped with the knowledge of how to design safe and effective resistance training programs. In order to spur continued improvement, minimize the chance of injury, achieve client compliance, and minimize the chance of overtraining, all exercise programs should be based on upon three main principles – specificity, progression, and overload. The goal […]

Top 5 tips to improve the vertical jump

Top 5 tips to improve the vertical jump by Charles Poliquin 1. Give priority to glutes and hamstrings

 Train the posterior chain: Biomechanists have estimated that the glutes and hamstrings contribute respectively 40% and 25% of one’s height in vertical jump test. It is of my opinion that driving up poundages in basic pulling strength […]

6-12-25 rep scheme

The 6-12-25 drop set rep scheme (43 total reps in the set) includes rep ranges that vary from relative strength, to hypertrophy, and finally to muscle endurance. Combining the three into one mega drop set with short rest periods make this one way to get out of a strength or hypertrophy rut. If you’re short […]

Quick Hits: Barbell Squat Form

The squat and its variations are at the foundation of many of the programs I design for a variety of clientele. One of the common form faults that I find in trainees during the barbell back squat is the end of the bar traveling in front the front of the foot during the eccentric phase […]

Quick Hits: Rep Schemes – Wave Loading

The manipulation of reps, set, and load/intensity is an important consideration when designing fitness programs. The good ole 3 x 12 rep scheme may work if you’re a novice, but it’s simply doesn’t provide the stimulus needed for hypertrophy or strength gains for those with more lifting experience. The idea of wave loading takes advantage […]

Posture and Performance

From my experience, steps are often missed in the name of either ignorance or in the attempt to please client or athlete demands when someone is starting an exercise or sport performance program. If you have a building that wasn’t structurally sound, would you pile people into it? How about if you have a car […]

Improving lifting speed with a unique weightlifting method

For Your Consideration: Plyometric Olympic Lifts Improving lifting speed with a unique weightlifting method by Charles Poliquin One of the interesting aspects of the sport of weightlifting is that there are many methods that have produced champions. You have the extreme of the Bulgarians, who pretty much just do the two lifts and squats; the […]

A Nutrition Paradox

The commonly held idea is that obesity or excess fat accumulation is simply to due to excess energy consumption. Obesity is seen as a result of too much food consumption, gluttony, and too little activity. The solution is to consume less calories and exercise more to burn more energy. Eat less, move move, lose fat. […]

Muscle Fiber Composition: Effects on Program Design

An understanding of the predominant fiber composition of skeletal muscle can prove useful when designing an exercise program particularly with regards to chosing the appropriate load/intensity, rest period, set/rep parameters, & time under tension to create the optimal training effect. In simplified terms, certain muscles are predominantly designed for low force production but excellent endurance […]

Is Your Fitness Program Multi-Planar?

We function in an unstable, 3D environment. The human body is capable of moving into an infinite number of positions. Your training program should reflect this human ability to move freely within the three planes of motion. The three planes are as follows: 1. Sagittal Plane – divides the body into left and right halves […]

Primal Movement Patterns

Every good exercise program has a foundation. The strength of the foundation will ultimately determine the how strong of a structure the trainee can build. A weak foundation will ultimately result in a sub-par performance and potentially injury. A strong foundation will provide the needed base to unleash optimal performance and keep a trainee injury […]