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Vegetarians have smaller brains

by Barry Groves Source If you want to get ahead, get a brain There is overwhelming evidence that we can not be a vegetarian species. In 1972 the publication of two independent investigations confirmed this.[1] [2] They concerned fats. About half our brain and nervous system is composed of complicated, long-chain, fatty acids. These are […]

PUFA, Inflammation, and Rheumatoid Arthritis

Eur J Med Res. 2003 Aug 20;8(8):381-7. Dietary fatty acids and immune reactions in synovial tissue. Adam O. Inflammation of the synovial membrane in rheumatoid arthritis is mediated by specialized cells necessary for immune response. The most prominent features are the accumulation of mononuclear phagocytes, lymphocytes and leukocytes in the proliferating tissue. Pro-inflammatory and proliferative […]

Israeli Paradox: High Omega -6 Diet Promotes Disease

Also see: Unsaturated Fats, Oxidative Stress, and Atherosclerosis Unsaturated Fats and Heart Damage Maternal PUFA Intake Increases Breast Cancer Risk in Female Offspring PUFA Promote Cancer Toxicity of Stored PUFA Dietary PUFA Reflected in Human Subcutaneous Fat Tissue Arachidonic Acid’s Role in Stress and Shock Omega 6 Content of Common Foods by Matt Stone Isr […]

PUFA, Estrogen, Obesity and Early Onset of Puberty

Also see: Fat Tissue and Aging – Increased Estrogen Estrogen Related to Loss of Fat Free Mass with Aging Maternal Ingestion of Tryptophan and Cancer Risk in Female Offspring Childhood conditions influence adult progesterone levels Article on subject: Obesity and Family Stress Blamed As Girls As Young As Five Reaching Puberty Quotes by Ray Peat, […]

Maternal PUFA Intake Increases Breast Cancer Risk in Female Offspring

Also see: Hormonal profiles in women with breast cancer PUFA Promote Cancer PUFA Inhibit Glucuronidation PUFA Increases Estrogen PUFA, Estrogen, Obesity and Early Onset of Puberty Prenatal Exposure to Radiation Increases Cancer Risk Maternal Ingestion of Tryptophan and Cancer Risk in Female Offspring Israeli Paradox: High Omega -6 Diet Promotes Disease Elevated gestational estrogen and […]

Glycolysis Inhibited by Palmitate

Also see: Aldosterone, Sodium Deficiency, and Insulin Resistance Diabetes: Conversion of Alpha-cells into Beta-cells Free Fatty Acid Suppress Cellular Respiration Women, Estrogen, and Circulating DHA Insulin Inhibits Lipolysis The Randle Cycle Comparison: Carbon Dioxide v. Lactic Acid Carbon Dioxide Basics Carbon Dioxide as an Antioxidant Comparison: Oxidative Metabolism v. Glycolytic Metabolic Promoters of Efficient v. […]

PUFA Decrease Cellular Energy Production

Also see: PUFA – Accumulation & Aging Free Fatty Acids Suppress Cellular Respiration PUFA Breakdown Products Depress Mitochondrial Respiration “Curing” a High Metabolic Rate with Unsaturated Fats Fat Deficient Animals – Activity of Cytochrome Oxidase Randle Cycle Protective “Essential Fatty Acid Deficiency” Errors in Nutrition: Essential Fatty Acids ATP Regulates Cell Water “With aging, cells […]

10 Tips for Better Sleep

Also see: Better Sleep by Chris Masterjohn, PhD Sleep and Brain Energy Levels: ATP changes during sleep Quotes by Ray Peat, PhD: “Good sleep requires fairly vigorous metabolism and a normal body temperature. In old age, the metabolic rate is decreased, and sleep becomes defective.” “Since glucose and salt are used to treat shock (intravenous […]

Hypothyroidism, Intestinal Bacterial Overgrowth, & Lactose Intolerance

Also see: Autoimmunity and Intestinal Flora Lactose Intolerance, Starch, Fructose, Sucrose, & Thyroid Status Ray Peat, PhD on the Benefits of the Raw Carrot The effect of raw carrot on serum lipids and colon function Protective Bamboo Shoots Fermentable Carbohydrates, Anxiety, Aggression Courtesy of Danny Roddy’s Work: “The gastrointestinal tract is particularly sensitive to general […]

Autoimmunity, Thyroiditis, and Intestinal Flora

Also see: Ray Peat, PhD on the Benefits of the Raw Carrot How does estrogen enhance endotoxin toxicity? Let me count the ways. Autoimmune Disease and Estrogen Connection The effect of raw carrot on serum lipids and colon function Protective Bamboo Shoots Endotoxin: Poisoning from the Inside Out Hypothyroidism, Intestinal Bacterial Overgrowth, & Lactose Intolerance […]

Ben Goldacre: Battling bad science

Also see: What Doctors Don’t Know About the Drugs They Prescribe So I’m a doctor, but I kind of slipped sideways into research, and now I’m an epidemiologist. And nobody really knows what epidemiology is. Epidemiology is the science of how we know in the real world if something is good for you or bad […]

180 Program Testimonial – Follow Up – Smarter Not Harder

Female, age 32, VA & CA How has the continued use of the 180 Program nutrition principles helped you? It’s been 18 months since I started the 180 program. The following are benefits that I’ve experienced since beginning and maintaining this way of life: Weight loss (formerly a size 8, I am now a size […]

The Truth about Low Cholesterol

Also see: High Cholesterol and Metabolism Thyroid Status and Oxidized LDL Inflammatory TSH “Normal” TSH: Marker for Increased Risk of Fatal Coronary Heart Disease Thyroid Status and Cardiovascular Disease The Cholesterol and Thyroid Connection High Blood Pressure and Hypothyroidism A Cure for Heart Disease Hypothyroidism and A Shift in Death Patterns Low Blood Cholesterol Compromises […]

Unsaturated Fats and Age Pigment

Also see: Foods That Prevent Aging Skin by Emma Sgourakis “An editorial by Pinckney in the June 1973 issue of the American Heart Journal reviews evidence that the unsaturated fats hasten aging of the skin, are toxic to the both animals and man, and furthermore, that use of such diets has not prevented heart attack.” […]

Toxicity of Stored PUFA

Also see: Fats, functions & malfunctions Vitamin E Needs Increases with PUFA Consumption and Greater Unsaturation Dietary PUFA Reflected in Human Subcutaneous Fat Tissue Israeli Paradox: High Omega -6 Diet Promotes Disease Thigh and Buttock Fat Depots more Unsaturated than Abdominal Fat Depots PUFA Accumulation & Aging PUFA Promote Stress Response; Saturated Fats Suppress Stress […]

Ray Peat, PhD on Aspirin

Also see: Aspirin and Exercise Benefits of Aspirin PUFA Promote Cancer Arachidonic Acid’s Role in Stress and Shock Sunburn, PUFA, Prostaglandins, and Aspirin Phospholipases, PUFA, and Inflammation Dietary PUFA Reflected in Human Subcutaneous Fat Tissue Toxicity of Stored PUFA PUFA – Accumulation and Aging Ray Peat, PhD Quotes on Therapeutic Effects of Niacinamide Altitude Sickness: […]

Estrogen, Endotoxin, and Alcohol-Induced Liver Injury

Also See Alcohol Consumption – Estrogen and Progesterone In Women How does estrogen enhance endotoxin toxicity? Let me count the ways. PUFA and Liver Toxicity; Protection by Saturated Fats Endotoxin: Poisoning from the Inside Out Estrogen and Liver Toxicity Single Bout of Binge Drinking Linked to Immune System Effects Estrogen makes the toxic-mediator-producing cells in the […]

Anti-Inflammatory Omega -9 Mead Acid (Eicosatrienoic acid)

Also see: “Curing” a High Metabolic Rate with Unsaturated Fats Fat Deficient Animals – Activity of Cytochrome Oxidase Errors in Nutrition: Essential Fatty Acids Protective “Essential Fatty Acid Deficiency” Toxicity of Stored PUFA PUFA Promote Stress Response; Saturated Fats Suppress Stress Response Protect the Mitochondria Quotes by Ray Peat, PhD: “Linoleic acid, linolenic acid, arachidonic […]

Arachidonic Acid’s Role in Stress and Shock

Also see: Resuscitation: Benefits of ATP, Glucose, and Sodium Trauma & Resuscitation: Toxicity of Lactated Ringer’s Solution Sunburn, PUFA, Prostaglandins, and Aspirin Phospholipases, PUFA, and Inflammation Dietary PUFA Reflected in Human Subcutaneous Fat Tissue Toxicity of Stored PUFA PUFA – Accumulation and Aging Brain Swelling Induced by Polyunsaturated Fats (PUFA) Fish Oil Toxicity Estrogen’s Role […]

Fats and AGEs: PUFAs Are Even Worse than Fructose

Source Olive oil is mostly monounsaturated fat. (Photo by Splat Worldwide) While the exact role AGEs play in aging is still unclear, it seems that reducing their accumulation in the body is a useful goal. And if for no other reason, how about being superficial: liver spots, for example, are a visible sign of AGEs in […]

“Curing” a High Metabolic Rate with Unsaturated Fats

Also see: Fat Deficient Animals – Activity of Cytochrome Oxidase Errors in Nutrition: Essential Fatty Acids Thumbs Up: Fructose Cardiolipin, Cytochrome Oxidase, Metabolism, & Aging Medium Chain Fats from Saturated Fat – Weight Management Friendly Toxicity of Stored PUFA Dietary PUFA Reflected in Human Subcutaneous Fat Tissue Israeli Paradox: High Omega -6 Diet Promotes Disease […]

Fat Deficient Animals – Activity of Cytochrome Oxidase

Also see: “Curing” a High Metabolic Rate with Unsaturated Fats Cardiolipin, Cytochrome Oxidase, Metabolism, & Aging Errors in Nutrition: Essential Fatty Acids Thumbs Up: Fructose PUFA Accumulation & Aging Toxicity of Stored PUFA Dietary PUFA Reflected in Human Subcutaneous Fat Tissue Israeli Paradox: High Omega -6 Diet Promotes Disease PUFA Accumulation & Aging Unsaturated Fats […]

Alcohol Consumption – Estrogen and Progesterone In Women

Also see: Estrogen, Endotoxin, and Alcohol-Induced Liver Injury How does estrogen enhance endotoxin toxicity? Let me count the ways. PUFA and Liver Toxicity; Protection by Saturated Fats Endotoxin: Poisoning from the Inside Out Fish Oils Increase Intestinal Permeability Estrogen and Liver Toxicity Single Bout of Binge Drinking Linked to Immune System Effects Alcohol and Alcoholism […]

Progesterone: Essential to Your Well-Being

By Raymond F. Peat, Ph. D. Editor’s Note: In her “Of Many Things” column this January, Betty Franklin introduced Dr. Raymond Peat’s work with natural progesterone, applied externally. Response from readers has been tremendous, so we invited Dr. Peat to write a follow-up, more comprehensive report on the subject. His doctorate, from the University of […]

Ray Peat, PhD on Thyroid, Temperature, Pulse, and TSH

Also see: Are biochemical tests of thyroid function of any value in monitoring patients receiving thyroxine replacement? W.D. Denckla, A.V. Everitt, Hypophysectomy, & Aging Temperature and Pulse Basics & Monthly Log The Cholesterol and Thyroid Connection Inflammation from Decrease in Body Temperature High Cholesterol and Metabolism The Truth about Low Cholesterol Thyroid Status and Oxidized […]