Browsing articles in "aging"
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Aging, infection, trauma, prolonged cortisol excess, somatostatin, dopamine or L-dopa, adrenaline (sometimes; Mannisto, et al., 1979), amphetamine, caffeine and fever can lower TSH, apart from the effect of feedback by the thyroid hormones, creating a situation in which TSH can appear normal or low, at the same time that there is a real hypothyroidism. -Ray [...]
Also see: “Normal” TSH: Marker for Increased Risk of Fatal Coronary Heart Disease Thyroid Insufficiency. Is Thyroxine the Only Valuable Drug? High T4 Concentrations in the Brain – Suppression of Brain Metabolism Assessment of the Thyroid: Achilles Tendon Reflex TSH has direct actions on many cell types other than the thyroid, and probably contributes directly [...]
Also See: Fat Tissue and Aging – Increased Estrogen Estrogen Levels Increase with Age A recent study (Toth, et al., 2000) shows that, at least in women, estrogen is closely associated with the general loss of fat-free tissue with aging. This shows a close association between the generalized atrophy of aging and the amount of [...]
Also see Exercise and Effect on Thyroid Hormone Metabolism, Brain Size, and Lifespan in Mammals Ray Peat, PhD: Quotes Relating to Exercise How strong is your resting metabolism? The resting metabolic rate (RMR) is responsible for 60 to 75% of daily energy expenditure (Poehlman, 1989). Energy expenditure from exercise is thus small relative to the [...]
Also see: Unsaturated Fats and Longevity “Curing” a High Metabolic Rate with Unsaturated Fats A living cell requires energy not only for all its functions, but also for the maintenance of its structure. -Albert Szent-Gyorgyi The brain has a high rate of oxidative metabolism, and so it forms a very large proportion of the carbon [...]
The gerontologist, V.V. Frolkis, recently found that mice lived 43% longer than animals on the standard diet when they periodically had activated charcoal added to their food. This is the clearest evidence I have seen that “bowel toxins” make a major contribution to the aging process. -Ray Peat, PhD Biomater Artif Cells Artif Organs. 1989;17(3):341-51. [...]
Also see: Fat Tissue and Aging – Increased Estrogen J Gerontol. 1978 Mar;33(2):191-6. Circulating plasma levels of pregnenolone, progesterone, estrogen, luteinizing hormone, and follicle stimulating hormone in young and aged C57BL/6 mice during various stages of pregnancy. Parkening TA, Lau IF, Saksena SK, Chang MC. Young (3-5 mo of age) and senescent (12-15 mo of [...]
On the level of the whole organism, stress causes overactivity of the pituitary, and removal of the pituitary extends life, and retards the hardening of the extracellular connective material (Everitt, et al., 1983). -Ray Peat, PhD Mech Ageing Dev. 1983 Jul-Aug;22(3-4):233-51. The anti-aging action of hypophysectomy in hypothalamic obese rats: effects on collagen aging, age-associated [...]
